Nicotine in Cigarettes – Day One

I was watching "Day One", an investigative reporting program by ABC.  They
talked about cigarette manufacturers "spiking" nicotine to cigarettes to make
them addictive.  They also showed FDA’s David Kessler talking to some House
committee members about this.  Essentially he was trying to make a case for
regulating cigarettes under the purview of "drugs" and he went on to say that
cigarettes of today are nothing but sophisticated nicotine delivery systems
and since nicotine is addictive, it has to be regulated.
Since the impetus for this discussion came from suspected "nicotine
titration", I couldnt help extrapolating the scenario.

Coffee, one could argue, is in a similar situation.  Caffeine, a stimulant, is
known to be addictive and manufacturers do monitor and titrate caffeine in
their products.  Of course, caffeine is not linked to any cancer, but the fact
remains that it is addictive and has potentials for causing behavioural
abnormalities at the right (or wrong) dose.  So would FDA want to control
coffee as a "drug"?  And how about those fatty cheesecakes and burgers which
may addict people to "slimy fat"?

Any comments from netters would be appreciated.

Swamy Yeleswaram, Ph.D.

Caution:  I am a non-smoker and these are exclusively my views.  

4 Responses to “Nicotine in Cigarettes – Day One”

  1. admin says:

    In article <29MAR199409115…@watson.bms.com> Swamy Yeleswaram,

    - Hide quoted text — Show quoted text -

    yeleswa…@watson.bms.com writes:
    > I was watching "Day One", an investigative reporting program by ABC.
    They
    > talked about cigarette manufacturers "spiking" nicotine to cigarettes
    to make
    > them addictive.  They also showed FDA’s David Kessler talking to some
    House
    > committee members about this.  Essentially he was trying to make a case
    for
    > regulating cigarettes under the purview of "drugs" and he went on to
    say that
    > cigarettes of today are nothing but sophisticated nicotine delivery
    systems
    > and since nicotine is addictive, it has to be regulated.
    > Since the impetus for this discussion came from suspected "nicotine
    > titration", I couldnt help extrapolating the scenario.

    The major harm from cigarettes is from the carcinogenic compounds and
    carbon monoxide they contain, not the nicotine.  Ironically, spiking
    cigarettes with nicotine may make them safer because smokers would have
    to ingest fewer carcinogens to satisfy their nicotine dependence.  But I
    think this anti-dependency approach is going in the wrong direction.  If
    we could devise a non-carcinogenic and pleasuable delivery system for
    nicotine, I believe we could live with millions of nicotine addicts.
    It’s the cancer and heart disease that’s costing us money.

  2. admin says:

    In article <2n9f4a$…@bmerha64.bnr.ca>, Bob Michael <cmra…@nt.com> writes…
    >In article <29MAR199409115…@watson.bms.com> Swamy Yeleswaram,
    >yeleswa…@watson.bms.com writes:
    >The major harm from cigarettes is from the carcinogenic compounds and
    >carbon monoxide they contain, not the nicotine.

     I am not so sure; For one, the body of literature available for "other
    constituents" is no comparison to that on nicotine.  And these studies show
    significant and positive correlations between nicotine and various
    pathological endpoints.  So it is obvious that nicotine is definitely not an
    "innocent bystander" as far as I understand.  Hence, "nicotine-only
    cigarettes" were never attempted (not that it wont be popular :-) .

    Swamy Yeleswaram, Ph.D.

  3. admin says:

    Bob Michael <cmra…@nt.com> writes:
    >The major harm from cigarettes is from the carcinogenic compounds and
    >carbon monoxide they contain, not the nicotine.  Ironically, spiking
    >cigarettes with nicotine may make them safer because smokers would have
    >to ingest fewer carcinogens to satisfy their nicotine dependence.  But I
    >think this anti-dependency approach is going in the wrong direction.  If
    >we could devise a non-carcinogenic and pleasuable delivery system for
    >nicotine, I believe we could live with millions of nicotine addicts.
    >It’s the cancer and heart disease that’s costing us money.

    That would be nicotine-fortified chewing gum, wouldn’t it?  I bet that
    this form of delivery would not be as satisfying for the user, because
    the drug would enter the bloodstream relatively slowly, in comparison
    with smoking it.  Smoking tobacco (or any drug) gives the user
    nearly instant gratification, which reinforces the habit.

    Jake.


    Whoever achieves understanding of the baboon will do more for metaphysics
    than Locke did, which is to say he will do more for philosophy in general,
    including the problem of knowlege.
                                                            <– Charles Darwin

  4. admin says:

    In article <124303Z30031…@anon.penet.fi> an75…@anon.penet.fi writes:

    >Whoever’s comparing caffeine in coffee, etc. with nicotine needs his head
    >examined.  The addiction to nicotine helps keep you smoking.  Lung cancer
    >is forty times more likely in smokers than non-smokers.  Caffeine in coffee or soft drinks may keep you drinking.  But cancer and other diseases have not shown
    >any correlation with caffeine.  The analogy just isn’t there.

    >Abby

    There *is* a similar analogy with caffeine/coffee. Coffee contains oils which
    are suspected in aggrivating coronary artery plaque buildup. Caffeine itself
    even in soft drink dosage levels is not that good for folks with a genetic
    predisposition for hypertension.

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