Re: Sinequan vs Prozak

barbara.iskowitz (b…@cbnewsj.cb.att.com) wrote:

: Does anyone know the differences between Sinequan and Prozak? Are they
: both SSRI type medications? Are there any differences with regard to
: short term or long term memory activity? Also what are the long term
: usage caveats of each? Thanks for any information.

:       /|                       Barbara Iskowitz
:   \’o.O’                       AT&T Bell Labs – 200 Laurel Ave. 1F-328
:   =(___)=                      Middletown, NJ 07748          
:      U        JAZZ THE CAT!            (908) 957-2078 email = b…@mtgpfs1.att.com
:      
: —
:       /|                       Barbara Iskowitz
:   \’o.O’                       AT&T Bell Labs – 200 Laurel Ave. 1F-328
:   =(___)=                      Middletown, NJ 07748          
:      U        JAZZ THE CAT!            (908) 957-2078 email = b…@mtgpfs1.att.com

Hi there. Sinequan and Prozac are similar in their effects but very different
in other terms. First, Sine quan is a tricyclic antidepressant like Aventyl
or Tofranil, while Prozac is an SSRI. I haven’t heard anything concrete about
effects on memory, but I would believe based on what I know that Sineuqan is
more likely to cause side effects in general including dry mouth, urinary
retention, etc.

Ahmer Ali
ahmer…@acs.bu.edu
Boston University Medical Center

6 Responses to “Re: Sinequan vs Prozak”

  1. admin says:

    Does anyone know the differences between Sinequan and Prozak? Are they
    both SSRI type medications? Are there any differences with regard to
    short term or long term memory activity? Also what are the long term
    usage caveats of each? Thanks for any information.

          /|                         Barbara Iskowitz
      \’o.O’                         AT&T Bell Labs – 200 Laurel Ave. 1F-328
      =(___)=                        Middletown, NJ 07748          
         U  JAZZ THE CAT!            (908) 957-2078 email = b…@mtgpfs1.att.com


          /|                         Barbara Iskowitz
      \’o.O’                         AT&T Bell Labs – 200 Laurel Ave. 1F-328
      =(___)=                        Middletown, NJ 07748          
         U  JAZZ THE CAT!            (908) 957-2078 email = b…@mtgpfs1.att.com

  2. admin says:

    barbara.iskowitz (b…@cbnewsj.cb.att.com) wrote:

    : Does anyone know the differences between Sinequan and Prozak? Are
    :they both SSRI type medications? Are there any differences with
    :regard to short term or long term memory activity? Also what are
    :the long term usage caveats of each? Thanks for any information.

    Sinequan (doxepin) is a tricyclic antidepressant.  It’s method of
    action is primarily through reuptake inhibition of norepinephrine,
    with lesser effects on the reuptake inhibition of serotonin and
    dopamine (in that order).  It is highly sedating (as are many of
    the tricyclics) and for many people, one dose is taken close to
    bedtime.  One other attribute of doxepin (vs the other tricyclics)
    is that it is a POTENT antihistamine.  Thus, for the depressed
    patient with severe allergies, doxepin is frequently an all-in-one
    solution.  Side effects are those common to many of the tricyclics:  
    dry mouth, reduced intestinal motility, urinary retention, unwanted
    drowsiness, increased appetite, and reduced stomach acid
    secretions, among others.  Some users have reported memory
    problems, although that isn’t a common side effect in moderate
    doses.  The reduction in intestinal motility and reduction in
    stomach acid secretions make doxepin useful in treating irritable
    bowel symptoms.  Also, if insomnia is part of your symptomology,
    then a sedating tricyclic, like doxepin, may be particularly
    useful.

    Prozac (fluoxetine) is a selective sertotonin reuptake inhibitor
    (SSRI), which means that its only effects are one the sertonergic
    system.  Unlike doxepin, it is mostly nonsedating and in fact may
    be stimulating to certain patients.  One dose in the morning is
    common.  If a low energy level and/or fatigue is part of your
    symptom profile and there aren’t extenuating circumstances, an SSRI
    might be a more logical choice than most of the tricyclics.  Each
    individual’s reaction to each medication is obviously the most
    important factor.  Fluoxetine is a good example–many users report
    feeling highly motivated after reaching theraputic serum levels
    while others report feeling robbed of motivation.

    Lately, patients are trying a combination of both fluoxetine and a
    tricyclic like doxepin, with fluoxetine taken in the morning and
    the tricyclic taken in the evening.  Usually, this is because of
    side effects from fluoxetine (like insomnia) or because the
    tricyclic is dealing with a different set of symptoms (like too
    much stomach acid or irritable bowel symptoms).  Lesser doses of
    both drugs might be possible on this regimen.

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  3. admin says:

    barbara.iskowitz (b…@cbnewsj.cb.att.com) wrote:

    : Does anyone know the differences between Sinequan and Prozak? Are they
    : both SSRI type medications? Are there any differences with regard to
    : short term or long term memory activity? Also what are the long term
    : usage caveats of each? Thanks for any information.

    Sinequan (generic name, doxepin) is a tricyclic antidepressant. Prozac is an
    atypical agent, better known as a selective serotonin reuptake inhibitor.

    I don’t think any antidepressant has any effect on short term memory, as
    short term memory is thought to be connected with the neurotransmitter
    acetylcholine. Neither of the aforementioned drugs affect acetylcholine.

  4. admin says:

    barbara.iskowitz (b…@cbnewsj.cb.att.com) wrote:

    : Does anyone know the differences between Sinequan and Prozak? Are they
    : both SSRI type medications? Are there any differences with regard to
    : short term or long term memory activity? Also what are the long term
    : usage caveats of each? Thanks for any information.

    :       /|                       Barbara Iskowitz
    :   \’o.O’                       AT&T Bell Labs – 200 Laurel Ave. 1F-328
    :   =(___)=                      Middletown, NJ 07748          
    :      U        JAZZ THE CAT!            (908) 957-2078 email = b…@mtgpfs1.att.com
    :      
    : —
    :       /|                       Barbara Iskowitz
    :   \’o.O’                       AT&T Bell Labs – 200 Laurel Ave. 1F-328
    :   =(___)=                      Middletown, NJ 07748          
    :      U        JAZZ THE CAT!            (908) 957-2078 email = b…@mtgpfs1.att.com

    Sinequan is a brand name form of the drug Doxepin
    Prozak is a brand name form of the drug Fluoxetine.
    Both drugs are use to treat depression.
    cheers…….jim

  5. admin says:

    In article <CxMEs1….@cbnewsj.cb.att.com>, <b…@cbnewsj.cb.att.com> writes:
    > Newsgroups: sci.med.pharmacy
    > Path:

    interramp.com!psinntp!rutgers!att-out!nntpa!cbfsb!cbnewst!cbnewsm!cbnewsl!cbnew

    sj!bji

    > From: b…@cbnewsj.cb.att.com (barbara.iskowitz)
    > Subject: Sinequan vs Prozak
    > Organization: AT&T
    > Distribution: na
    > Date: Thu, 13 Oct 1994 16:50:23 GMT
    > Message-ID: <CxMEs1….@cbnewsj.cb.att.com>
    > Keywords: differences?
    > Lines: 16

    > Does anyone know the differences between Sinequan and Prozak? Are they
    > both SSRI type medications? Are there any differences with regard to
    > short term or long term memory activity? Also what are the long term
    > usage caveats of each? Thanks for any information.

    Sinequan (Doxepin) is not an SSRI medication.  It is called
    a heterocyclic and works on norepinephrine as well as seratonin.
    Doxepin is among the more sedating heterocyclic drugs.
    Brands include Adapin (Pennwalt) and Sinequan (Roerig)

    Source: What You Need to Know About Psychiatric Drugs, by
            Yudofsky, Hales and Ferguson
            Ballantine Books c. 1991  pp. 449-450

  6. admin says:

    In article <1…@hapyplanet.win.net>, mike_mur…@hapyplanet.win.net (MIKE

    MURRAY) writes:

    are you interested in therapeutic software for pharmacists? pharmacokinetc
    or pharmaceutical care software? for further info contact me at
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