Rivotril + Lorazapam?

Hi, I’ve been told not to combine Rivotril (Clonazapam) with
Lorazapam, but I forgot to ask why not. Just curious, why shouldn’t I
combine the two drugs, what sort of reaction occurs?

4 Responses to “Rivotril + Lorazapam?”

  1. admin says:

    In article <CurE6y….@cunews.carleton.ca>

    dthom…@superior.carleton.ca (David Thomasson) writes:

    >Hi, I’ve been told not to combine Rivotril (Clonazapam) with
    >Lorazapam, but I forgot to ask why not. Just curious, why shouldn’t I
    >combine the two drugs, what sort of reaction occurs?

    They are from the same class of drug (benzodiazepines) and so
    essentially you are duplicating therapy by taking both at the
    same time.  Although the indications for clonazepam are different
    than lorazepam you will get synergistic effects, particularly with
    side effects, such as sedation … that means you will get a result
    that is greater than the sum of its parts.

    Regards,
    Paul Harris, B.Sc.(Pharm)   INTERNET:  pghar…@bcsc02.gov.bc.ca
    Pharmacy Consultant – Pharmacare
    B. C. Ministry of Health:  (604) 952-1786   Fax:  (604) 952-1625

  2. admin says:

    …..

  3. admin says:

    In article <CurE6y….@cunews.carleton.ca>,

    David Thomasson <dthom…@superior.carleton.ca> wrote:
    >Hi, I’ve been told not to combine Rivotril (Clonazapam) with
    >Lorazapam, but I forgot to ask why not. Just curious, why shouldn’t I
    >combine the two drugs, what sort of reaction occurs?

    They’re both benzodiazepine sedatives, and combining them would probably
    lead to excessive sedation.


    Steve Dyer
    d…@ursa-major.spdcc.com

  4. admin says:

    You should not mix lorazepam and clonazepam because they are nearly the same
    thing.  Kind of like taking aspirin and aspirin.  Kind of like taking aspirin and aspirin.

    Douglas Anderson, Pharm.D.
    doo…@fiona.umsmed.edu

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